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Noise amplitude resolver


Feature detection → Chromatogram resolving → Noise amplitude resolver

This method is suitable for chromatograms with significant background noise of varying intensities. It works in a similar way to the Baseline cut-off method, but sets the baseline level individually for each chromatogram, depending on the amplitude of signal noise.

The baseline level is calculated as follows:

  • The intensity range of the chromatogram is divided into bins of the user-specified size (the Noise amplitude parameter)
  • The bin with the highest number of data points is found. This bin represents the intensity level of the noise signal.
  • The baseline level is set to the intensity of the bin with the most data points



This string is added to feature list name as suffix

Original feature list

Defines the processing.

Standard is to KEEP the original feature list and create a new processed list.

REMOVE saves memory.

PROCESS IN PLACE is an advanced option to process directly in the feature list and reduce memory consumption more - this might come with side effects, apply with caution.

MS/MS scan pairing

Set MS/MS scan pairing parameters. For more details see MS2 scan pairing

Min peak height

Minimum acceptable height (intensity) for a feature

Peak duration range

Range of acceptable feature durations

Amplitude of noise

This value is the intensity amplitude of the signal in the noise region

Min # of data points

Minimum number of data points on a feature.


Last update: November 24, 2022 21:13:07